Endogenously labeled low density lipoprotein triglyceride and apoprotein B kinetics.
نویسندگان
چکیده
منابع مشابه
Dietary fish oil increases conversion of very low density lipoprotein apoprotein B to low density lipoprotein.
Dietary fish oils, which are rich in omega-3 fatty acids, are known to produce a marked lowering of very low density lipoprotein (VLDL) triglyceride concentrations, but they have a less marked effect on low density lipoprotein (LDL) cholesterol. Our previous apolipoprotein (apo) B kinetic studies in miniature pigs demonstrated that conversion of VLDL apo B to LDL apo B accounted for 15% to 20% ...
متن کاملCatabolism of very low density lipoprotein B apoprotein in man.
The turnover and the catabolic fate of the B apoprotein of very low density lipoprotein (VLDL-B) was studied in 15 normal and hyperlipidemic subjects using reinjected autologous VLDL labeled with radioiodine. The specific radioactivity-time curve of the B apoprotein in total VLDL (S(f)20-400) was multiexponential but conformed to a two-pool model during the first 48 h of catabolism. The flux wa...
متن کاملVery low density lipoprotein B-apoprotein kinetics in human subjects. relationships between pool size, flux, and removal rate.
متن کامل
Apolipoproteins C-III and A-V as predictors of very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics.
OBJECTIVE We investigated the associations between plasma very-low-density lipoprotein (VLDL)-apolipoprotein (apo)C-III and apoA-V concentrations and the kinetics of VLDL-apoB-100 and VLDL triglycerides in 15 men. We also explored the relationship between these parameters of VLDL metabolism and VLDL-apoC-III kinetics. METHODS AND RESULTS ApoC-III, apoB, and triglyceride kinetics in VLDL were ...
متن کاملLow-density-lipoprotein apoprotein B in plasma as measured by radial immunodiffusion and rocket immunoelectrophoresis.
Radial immunodiffusion (RID) and rocket immunoelectrophoresis (RIE) are compared with respect to determination of LDL-bound apo B in plasma. Isolated VLDL could not enter a 15 g/L agarose gel when either technique was used. However, in the presence of plasma proteins, migration of VLDL into agarose was enhanced. Only when plasma samples were kept frozen before the assay was plasma VLDL unable t...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1978
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)40681-9